Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809850 | 0.87 | MAPT (0.51) | ALDH1A1MTNR1AMTNR1BTBXAS1L3MBTL1 | |
| SCHEMBL7811371 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MTNR1AMTNR1BL3MBTL1KMT2A | |
| SCHEMBL7803269 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MTNR1AMTNR1BTBXAS1L3MBTL1 | |
| SCHEMBL7811788 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MTNR1AMTNR1BTBXAS1L3MBTL1 | |
| SCHEMBL7809757 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MTNR1AMTNR1BTBXAS1L3MBTL1 | |
| SCHEMBL7811305 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MTNR1AMTNR1BTBXAS1L3MBTL1 | |
| SCHEMBL21244819 | 0.78 | HDAC3 (0.54) | — | |
| SCHEMBL7815552 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MTNR1AMTNR1BTBXAS1L3MBTL1 | |
| SCHEMBL21245925 | 0.77 | MTNR1A (0.53) | ALDH1A1MTNR1AMTNR1BL3MBTL1KMT2A | |
| SCHEMBL11035940 | 0.76 | CYP11B1 (0.49) | ALDH1A1MTNR1AMTNR1BL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |