Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803269 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TBXAS1L3MBTL1KMT2AMTNR1A | |
| SCHEMBL7811305 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TBXAS1L3MBTL1KMT2AMTNR1A | |
| SCHEMBL7811788 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TBXAS1L3MBTL1KMT2AMTNR1A | |
| SCHEMBL7815552 | 0.99 | ALDH1A1 (0.46) | ALDH1A1TBXAS1L3MBTL1KMT2AMTNR1A | |
| SCHEMBL7803240 | 0.92 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7803259 | 0.88 | ACLY (0.46) | TBXAS1MAPT | |
| SCHEMBL7807915 | 0.82 | CNR2 (0.49) | ALDH1A1KMT2AMTNR1AMTNR1BCNR2 | |
| SCHEMBL7809850 | 0.81 | MAPT (0.51) | ALDH1A1TBXAS1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL7815436 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TBXAS1L3MBTL1KMT2AMTNR1A | |
| SCHEMBL7803002 | 0.78 | TBXAS1 (0.70) | TBXAS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |