SCHEMBL7816115

SCHEMBL7816115

COc1cc(-c2ccc(Cl)cc2)ccc1O

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CXCL12 P48061 4/20 0.65
ALOX5 P09917 2/20 0.59
ERN1 O75460 1/20 0.55
MAOA P21397 1/20 0.55
MAOB P27338 1/20 0.53
CSNK2A2 P19784 2/20 0.52
CSNK2B P67870 2/20 0.52
CSNK2A1 P68400 2/20 0.52
POLB P06746 1/20 0.51
FYN P06241 2/20 0.50
CXCR4 P61073 1/20 0.50
ACHE P22303 1/20 0.50
BACE1 P56817 1/20 0.50
RAF1 P04049 1/20 0.49
BRAF P15056 1/20 0.49
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
NTSR1 P30989 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4386820 0.90 MAOB (0.64) CXCL12ALOX5MAOBPOLBFYN
SCHEMBL3693339 0.88 MAOB (0.67) CXCL12ALOX5MAOBPOLBFYN
SCHEMBL3813200 0.84 MAOB (0.69) ALOX5ERN1MAOBCSNK2A2CSNK2B
SCHEMBL18121551 0.84 MAOB (0.57) ALOX5ERN1MAOBPOLBFYN
SCHEMBL9622952 0.84 MAOB (0.69) ALOX5ERN1MAOBCSNK2A2CSNK2B
SCHEMBL363972 0.84 MAOB (0.61) CXCL12MAOBCSNK2A2CSNK2BCSNK2A1
SCHEMBL30957832 0.82 POLB (0.62) ALOX5MAOAMAOBPOLBFYN
SCHEMBL2524920 0.82 POLB (0.62) ALOX5MAOAMAOBPOLBFYN
SCHEMBL8338706 0.82 FYN (0.61) CXCL12ALOX5MAOBCSNK2A2CSNK2B
SCHEMBL12477879 0.82 APP (0.61) ALOX5MAOBPOLBFYNPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553623-B1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL CO (JP) 2001-04-04 EP disclosed
US-5556867-A INSECTICIDES AND MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
US-5411979-A Insecticides, miticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-05-02 US disclosed
EP-0553623-A1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-04 EP disclosed