SCHEMBL363972

SCHEMBL363972

COc1cc(Cl)ccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.61
CXCL12 P48061 4/20 0.58
AR P10275 1/20 0.54
SLC22A6 Q4U2R8 1/20 0.53
SLC22A8 Q8TCC7 1/20 0.53
MEN1 O00255 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53
TRPA1 O75762 1/20 0.52
TRIM24 O15164 1/20 0.52
ALDH1A1 P00352 1/20 0.52
HPGD P15428 1/20 0.52
ALDH5A1 P51649 1/20 0.52
ABAT P80404 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
TRIM33 Q9UPN9 1/20 0.52
HTT P42858 1/20 0.52
APP P05067 1/20 0.51
CXCR4 P61073 1/20 0.51
TSHR P16473 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL27485393 0.94 MAOB (0.55) MAOBCXCL12ARSLC22A6SLC22A8
Formic Acid SCHEMBL27641585 0.90 TRIM24 (0.58) MAOBCXCL12ARSLC22A6SLC22A8
SCHEMBL19425624 0.86 SLC6A2 (0.50) MAOBCXCL12ARKMT2AHPGD
SCHEMBL16185272 0.85 CXCL12 (0.46) MAOBCXCL12ARSLC22A6SLC22A8
SCHEMBL7816115 0.84 CXCL12 (0.65) MAOBCXCL12CXCR4CSNK2A2CSNK2B
SCHEMBL31142480 0.82 MAPT (0.59) MEN1KMT2AALDH1A1HPGDTDP1
SCHEMBL541591 0.82 MAPT (0.59) MEN1KMT2AALDH1A1HPGDTDP1
SCHEMBL27758491 0.79 CALM1 (0.66) ARALDH1A1TDP1TSHRCA2
SCHEMBL5317115 0.79 NFE2L2 (0.73) CXCL12ARAPPCXCR4CA2
SCHEMBL2951837 0.79 NFE2L2 (0.73) CXCL12ARAPPCXCR4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240417568-A1 ADHESION PROMOTER FOR COMPOSITES AND METHODS THEREOF THE BOEING COMPANY (US) 2024-12-19 US claimed
EP-4477720-A1 ADHESION PROMOTER FOR COMPOSITES AND METHODS THEREOF The Boeing Company (US) 2024-12-18 EP claimed
US-20220372008-A1 LUCIFERIN DERIVATIVES AND A METHOD FOR SYNTHESIS THEREOF VIDYASIRIMEDHI INSTITUTE OF SCIENCE AND TECHNOLOGY (TH) 2022-11-24 US claimed
CN-111454132-A Method for synthesizing eugenol 江西恒诚天然香料油有限公司 2020-07-28 CN claimed
CN-105503626-A Synthesis method of 2-amino-4-chloro-6-metoxyphenol UNIV CHANGZHOU 2016-04-20 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
US-5149858-A Reacting with chlorine gas in presence of organic cation catalysts RHONE-POULENC CHIMIE (FR) 1992-09-22 US claimed
EP-0216714-B1 PROCESS FOR THE SELECTIVE CHLORINATION OF PHENOLIC COMPOUNDS RHONE-POULENC CHIMIE (FR) 1992-05-13 EP claimed
EP-0299891-B1 PROCESS FOR THE SELECTIVE CHLORINATION OF PHENOLIC COMPOUNDS RHONE-POULENC CHIMIE (FR) 1991-12-11 EP claimed
US-4876396-A AT ORTHO POSITION TO HYDROXYL; AMINE CATALYSTS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1989-10-24 US claimed
EP-3704094-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-03-11 EP disclosed
US-20260001861-A1 PYRIDINE CARBOXAMIDE COMPOUNDS FOR INHIBITING NAV1.8 LIEBER INST INC (US) 2026-01-01 US disclosed
US-12429417-B2 Devices, systems, and methods for agrochemical detection and agrochemical compositions SPOGEN BIOTECH, INC. (US) 2025-09-30 US disclosed
US-12421193-B2 GPR52 modulators and methods of use NEUROCRINE BIOSCIENCES, INC. (US) 2025-09-23 US disclosed
US-3980659-A INSECTICIDES, INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed
US-3956294-A AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed
US-3954782-A 2,6-Hydrazino-3-pyridine carboxyamides CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed
US-3947463-A Certain 2-amino-nicotinonitrile derivatives CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-30 US disclosed
US-3946024-A INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001861-A1 PYRIDINE CARBOXAMIDE COMPOUNDS FOR INHIBITING NAV1.8 SCN8A, SCN1A, SCN1B MAOB 987/4885CXCL12 4335/4885AR 3734/4885
US-20220372008-A1 LUCIFERIN DERIVATIVES AND A METHOD FOR SYNTHESIS THEREOF NQO1, DDT, GLO1 MAOB 52/4885CXCL12 3201/4885AR 4387/4885
US-12421193-B2 GPR52 modulators and methods of use GPR52, GPR68, GPR35 MAOB 947/4885CXCL12 3098/4885AR 743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.