Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980734 | 0.91 | KCNA5 (0.43) | MMP1MMP13MMP8MMP2MMP3 | |
| SCHEMBL6981814 | 0.90 | MMP1 (0.42) | MMP1MMP13MMP8CYP3A4CYP2D6 | |
| SCHEMBL6982700 | 0.90 | MMP1 (0.42) | MMP1MMP13MMP8CYP3A4CYP2D6 | |
| SCHEMBL6980811 | 0.86 | MMP1 (0.44) | MMP1MMP13MMP8MMP2MMP3 | |
| SCHEMBL6982289 | 0.84 | MMP1 (0.37) | MMP1MMP13 | |
| SCHEMBL6978664 | 0.81 | KCNA5 (0.38) | MMP1MMP13MMP2MMP3MMP7 | |
| SCHEMBL6985193 | 0.81 | MMP1 (0.50) | MMP1MMP13MMP8MMP2MMP3 | |
| SCHEMBL6988045 | 0.78 | CYP26A1 (0.38) | CYP3A4CYP2D6 | |
| SCHEMBL6985388 | 0.78 | MMP1 (0.38) | MMP1MMP13MMP8CYP3A4CYP2D6 | |
| SCHEMBL6979855 | 0.78 | MMP1 (0.38) | MMP1MMP13MMP8MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089964-A1 | HYDRAZINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000000465-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-01-06 | — | — | WO | disclosed |