Benzyl Bromide

Benzyl Bromide

SCHEMBL7816396

BrCc1ccccc1.O=c1c(Br)c(Br)cnn1Cc1ccccc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.49
MAPT P10636 8/20 0.49
HTT P42858 7/20 0.49
SMN1; SMN2 Q16637 6/20 0.49
NPC1 O15118 6/20 0.49
RAB9A P51151 6/20 0.49
LMNA P02545 6/20 0.49
NPSR1 Q6W5P4 6/20 0.49
PAX8 Q06710 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
PFKFB3 Q16875 1/20 0.47
HPGD P15428 5/20 0.47
S1PR4 O95977 4/20 0.47
S1PR1 P21453 4/20 0.47
XBP1 P17861 2/20 0.47
HSP90AA1 P07900 1/20 0.47
TLR9 Q9NR96 1/20 0.47
MITF O75030 2/20 0.47
PPARG P37231 3/20 0.45
NCOA2 Q15596 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4047300 0.94 ALDH1A1 (0.54) ALDH1A1MAPTHTTSMN1; SMN2NPC1
SCHEMBL2893856 0.80 ALDH1A1 (0.50) ALDH1A1MAPTHTTSMN1; SMN2NPC1
SCHEMBL6604659 0.79 PFKFB3 (0.52) ALDH1A1MAPTHTTSMN1; SMN2LMNA
SCHEMBL3985633 0.79 RAB9A (0.61) ALDH1A1MAPTHTTSMN1; SMN2NPC1
SCHEMBL12115553 0.79 ALDH1A1 (0.61) ALDH1A1MAPTHTTSMN1; SMN2NPC1
SCHEMBL18979949 0.77 RAB9A (0.67) ALDH1A1MAPTHTTSMN1; SMN2NPC1
SCHEMBL4184723 0.77 ALDH1A1 (0.62) ALDH1A1MAPTHTTSMN1; SMN2LMNA
SCHEMBL4178254 0.75 ALDH1A1 (0.61) ALDH1A1MAPTHTTSMN1; SMN2RAB9A
SCHEMBL6232549 0.75 BPTF (0.49) ALDH1A1MAPTHTTSMN1; SMN2RAB9A
SCHEMBL1311870 0.75 NPBWR1 (0.63) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124804-A1 PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS ABBOTT LABORATORIES (US) 2001-08-22 EP disclosed
WO-2000024719-A1 PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS ABBOTT LABORATORIES (US) 2000-05-04 WO disclosed