SCHEMBL7816561

SCHEMBL7816561

CC(=O)Oc1cc2ccccc2c2c1OC(c1ccc3c(c1)CCO3)(c1ccccc1F)C=C2

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
CTNNB1 P35222 1/20 0.32
WNT3A P56704 1/20 0.32
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8782282 0.86 ALDH1A1 (0.34) CHRM5
SCHEMBL8782703 0.83 GPR84 (0.34) NPC1RAB9ACHRM5
SCHEMBL12316024 0.83 CHRM5 (0.37) CHRM5
SCHEMBL1387752 0.81 NPC1 (0.35) CTNNB1WNT3ANPC1POLBRAB9A
SCHEMBL8782577 0.77 ALDH1A1 (0.35)
SCHEMBL1388004 0.77 DPP4 (0.33) FNTAFNTBPOLB
SCHEMBL7888138 0.76 HTT (0.36) NPC1POLBRAB9A
SCHEMBL8782492 0.75 HTT (0.36) NPC1POLBRAB9A
SCHEMBL8782497 0.74 TSHR (0.36) NPC1RAB9A
SCHEMBL1387780 0.73 KDM4E (0.36) FNTAFNTBCTNNB1WNT3ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9857882-B2 Pointing display device DONGWOO FINE-CHEM CO., LTD. (KR) 2018-01-02 US claimed
US-10754211-B2 Display device and manufacturing method thereof SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-25 US disclosed
EP-3299873-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF Samsung Display Co., Ltd. (KR) 2018-03-28 EP disclosed
US-20180081225-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-22 US disclosed
US-9857882-B2 Pointing display device DONGWOO FINE-CHEM CO., LTD. (KR) 2018-01-02 US disclosed
US-20150198745-A1 POINTING DISPLAY DEVICE DONGWOO FINE-CHEM CO., LTD (KR) 2015-07-16 US disclosed
WO-2014030943-A1 POINTING DISPLAY DEVICE 동우 화인켐 주식회사 (KR) 2014-02-27 WO disclosed
EP-0704067-B1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG IND OHIO INC (US) 2001-08-01 EP disclosed
EP-0704067-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1996-04-03 EP disclosed
EP-0704067-A4 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES INC (US) 1996-02-02 EP disclosed
US-5458815-A Photochromic naphthopyran compounds TRANSITIONS OPTICAL, INC. (US) 1995-10-17 US disclosed
US-5384077-A Naphthopyrans TRANSITIONS OPTICAL, INC. (US) 1995-01-24 US disclosed
WO-1995000866-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1995-01-05 WO disclosed