SCHEMBL1387780

SCHEMBL1387780

COc1ccccc1C1(c2ccc3c(c2)CCO3)C=Cc2c(ccc3ccccc23)O1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ERN1 O75460 1/20 0.32
NPBWR1 P48145 1/20 0.31
ABCB1 P08183 1/20 0.31
ABCC1 P33527 1/20 0.31
ABCG2 Q9UNQ0 1/20 0.31
CTNNB1 P35222 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1387752 0.85 NPC1 (0.35) KDM4EMEN1NPC1ALDH1A1LMNA
SCHEMBL1387871 0.84 NPC1 (0.38) KDM4EMEN1NPC1ALDH1A1LMNA
SCHEMBL1388004 0.81 DPP4 (0.33) KDM4EMEN1ALDH1A1LMNAGAA
SCHEMBL7128002 0.79 MAPT (0.36) KDM4EMEN1NPC1ALDH1A1LMNA
SCHEMBL5182208 0.76 MAPT (0.37) KDM4EMEN1NPC1ALDH1A1LMNA
SCHEMBL29613249 0.76 MAPT (0.37) KDM4EMEN1NPC1ALDH1A1LMNA
SCHEMBL7818669 0.75 MAPT (0.35) KDM4EMEN1NPC1ALDH1A1LMNA
SCHEMBL3929015 0.74 HTT (0.39) KDM4EMEN1NPC1ALDH1A1LMNA
SCHEMBL7821439 0.74 NPC1 (0.37) KDM4EMEN1NPC1ALDH1A1LMNA
SCHEMBL7816561 0.73 FNTA (0.33) NPC1FNTAFNTBCTNNB1WNT3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9857882-B2 Pointing display device DONGWOO FINE-CHEM CO., LTD. (KR) 2018-01-02 US claimed
EP-0704067-B1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG IND OHIO INC (US) 2001-08-01 EP claimed
JP-H08512031-A 1996-12-17 JP claimed
EP-0704067-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1996-04-03 EP claimed
EP-0704067-A4 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES INC (US) 1996-02-02 EP claimed
US-5384077-A Naphthopyrans TRANSITIONS OPTICAL, INC. (US) 1995-01-24 US claimed
WO-1995000866-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1995-01-05 WO claimed
US-10754211-B2 Display device and manufacturing method thereof SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-25 US disclosed
EP-3299873-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF Samsung Display Co., Ltd. (KR) 2018-03-28 EP disclosed
US-20180081225-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-22 US disclosed
US-9857882-B2 Pointing display device DONGWOO FINE-CHEM CO., LTD. (KR) 2018-01-02 US disclosed
US-20150198745-A1 POINTING DISPLAY DEVICE DONGWOO FINE-CHEM CO., LTD (KR) 2015-07-16 US disclosed
WO-2014030943-A1 POINTING DISPLAY DEVICE 동우 화인켐 주식회사 (KR) 2014-02-27 WO disclosed
EP-0704067-B1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG IND OHIO INC (US) 2001-08-01 EP disclosed
EP-0704067-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1996-04-03 EP disclosed
EP-0704067-A4 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES INC (US) 1996-02-02 EP disclosed
US-5458815-A Photochromic naphthopyran compounds TRANSITIONS OPTICAL, INC. (US) 1995-10-17 US disclosed
US-5384077-A Naphthopyrans TRANSITIONS OPTICAL, INC. (US) 1995-01-24 US disclosed
WO-1995000866-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1995-01-05 WO disclosed