Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825051 | 0.77 | LMNA (0.33) | HTR2CHTR2BPARP1 | |
| SCHEMBL9124282 | 0.71 | MAPT (0.38) | PARP1 | |
| SCHEMBL7830015 | 0.69 | HTR2C (0.41) | HTR2CHTR2BHTR2ADRD2SLC6A2 | |
| SCHEMBL2288761 | 0.67 | PARP1 (0.39) | HTR2CHTR2BPARP1 | |
| SCHEMBL14760157 | 0.66 | HTR2A (0.39) | HTR2CHTR2BHTR2ADRD2SLC6A2 | |
| SCHEMBL7830334 | 0.65 | HTR2A (0.33) | HTR2CHTR2ADRD2SLC6A2SLC6A4 | |
| SCHEMBL258234 | 0.64 | PARP1 (0.36) | HTR2CHTR2BPARP1 | |
| SCHEMBL1697644 | 0.64 | PARP1 (0.36) | HTR2APARP1 | |
| SCHEMBL7882155 | 0.64 | PARP1 (0.36) | HTR2CHTR2BPARP1 | |
| SCHEMBL1725344 | 0.64 | PARP1 (0.36) | HTR2CHTR2BPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712845-B1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5633248-A | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS, DIARYLALKYLIDENEDIAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0712845-A1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |