Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812680 | 0.83 | ALOX5 (0.46) | ALOX5IRAK4 | |
| SCHEMBL7803741 | 0.82 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL7813031 | 0.76 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL536722 | 0.75 | HCRTR1 (0.41) | IRAK4 | |
| SCHEMBL20416874 | 0.74 | IRAK4 (0.34) | IRAK4 | |
| SCHEMBL2037282 | 0.73 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL23355664 | 0.72 | IRAK4 (0.33) | IRAK4 | |
| SCHEMBL20436450 | 0.72 | KCNH2 (0.34) | IRAK4 | |
| SCHEMBL9375328 | 0.72 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL21790628 | 0.71 | ADORA2A (0.43) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788497-B1 | BISARYLCARBINOL DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC (CA) | 2001-05-23 | — | — | EP | disclosed |
| US-5552437-A | ANTIASTHMATIC, ANTIALLERGIC, ANTIINFLAMMATORY, AND CYTOPROTECTIVE AGENTS | MERCK FROSST CANADA, INC. (CA) | 1996-09-03 | — | — | US | disclosed |
| WO-1996013500-A1 | BISARYLCARBINOL DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1996-05-09 | — | — | WO | disclosed |