Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7890748 | 0.83 | CYP1A1 (0.55) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13679387 | 0.82 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL28997137 | 0.82 | POLB (0.62) | POLBTGM2MAPTHDAC3HDAC1 | |
| SCHEMBL9113346 | 0.81 | MAOB (0.45) | POLBTGM2MAPTALDH1A1MEN1 | |
| SCHEMBL12803387 | 0.81 | ALDH1A1 (0.53) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28444124 | 0.81 | TGM2 (0.59) | POLBTGM2MAPTHDAC3HDAC1 | |
| SCHEMBL2576588 | 0.81 | MAOB (0.61) | TGM2MAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL3831442 | 0.81 | L3MBTL1 (0.63) | TGM2MAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL23081898 | 0.80 | MAOB (0.44) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28954825 | 0.80 | TRPV1 (0.46) | POLBMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106431868-A | Method for synthesizing 4-bromoacetophenone being aminomethylbenzoic acid drug intermediate | 厦门莱恩斯特信息科技有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106431903-A | Synthesis method for 1,2,4-triacetoxybenzene serving as Catalin medical intermediate | 厦门莱恩斯特信息科技有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106431903-A | Synthesis method for 1,2,4-triacetoxybenzene serving as Catalin medical intermediate | 厦门莱恩斯特信息科技有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105483749-A | Method for electro-synthesizing 3-amido-2-thio-cyano-alpha, beta-unsaturated carbonyl compound in pairs | UNIV BEIJING TECHNOLOGY | 2016-04-13 | — | — | CN | disclosed |
| EP-1124810-A1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026202-A1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-05-11 | — | — | WO | disclosed |