Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ABCC9 | O60706 | 13/20 | 0.53 |
| ▸ | ABCC8 | Q09428 | 13/20 | 0.53 |
| ▸ | KCNJ11 | Q14654 | 13/20 | 0.53 |
| ▸ | KCNJ8 | Q15842 | 13/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832437 | 0.90 | GPR174 (0.59) | GPR174KDM4EMEN1LMNATSHR | |
| SCHEMBL7820326 | 0.84 | ALDH1A1 (0.67) | GPR174KDM4EMEN1KMT2AABCC9 | |
| SCHEMBL7817859 | 0.84 | ALDH1A1 (0.63) | GPR174KDM4EMEN1KMT2AABCC9 | |
| SCHEMBL7817258 | 0.83 | GPR174 (0.72) | GPR174MEN1KMT2AABCC9ABCC8 | |
| SCHEMBL1002731 | 0.83 | ABCC9 (0.73) | GPR174KDM4EKMT2AABCC9ABCC8 | |
| SCHEMBL22388478 | 0.83 | GPR174 (1.00) | GPR174MEN1KMT2A | |
| SCHEMBL15435890 | 0.83 | GPR174 (0.91) | GPR174MEN1KMT2A | |
| SCHEMBL7833345 | 0.83 | ABCC9 (0.75) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7836312 | 0.82 | ABCC9 (0.66) | GPR174MEN1KMT2AABCC9ABCC8 | |
| SCHEMBL15450429 | 0.78 | GPR174 (0.70) | GPR174MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |
| EP-0665834-B1 | QUINOLONE AND ACRIDINONE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | ASTRAZENECA AB (SE) | 2001-05-30 | — | — | EP | disclosed |
| US-5622964-A | ADMINISTERING 4,6,7,8-TETRAHYDRO-5(1H)-QUINOLONE DERIVATIVE TO TREAT ASTHMA IN MAMMALS | ZENECA LIMITED (GB) | 1997-04-22 | — | — | US | disclosed |
| US-5455253-A | For urinary incontinence | ZENECA LIMITED (GB) | 1995-10-03 | — | — | US | disclosed |
| EP-0665834-A1 | QUINOLONE AND ACRIDINONE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | ZENECA LIMITED (GB) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994008966-A1 | QUINOLONE AND ACRIDINONE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | ZENECA LIMITED (GB) | 1994-04-28 | — | — | WO | disclosed |