Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030632 | 0.87 | ALDH1A1 (0.65) | GAAALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13685522 | 0.84 | ALDH1A1 (0.50) | GAAALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13685529 | 0.82 | KDM4E (0.55) | GAAALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13685417 | 0.80 | KDM4E (0.52) | GAAALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13685506 | 0.80 | KDM4E (0.52) | GAAALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13685542 | 0.80 | KDM4E (0.52) | GAAALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13685546 | 0.80 | KDM4E (0.52) | GAAALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13236491 | 0.80 | ALDH1A1 (0.59) | GAAALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13685590 | 0.77 | KDM4E (0.50) | GAAALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7817348 | 0.77 | MET (0.59) | GAAALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | claimed |
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |