Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.59 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | PRNP | P04156 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820657 | 0.94 | KDM4E (0.61) | METRPS6KA3SMN1; SMN2POLBMAPK1 | |
| SCHEMBL7814851 | 0.91 | ALDH1A1 (0.60) | METRPS6KA3SMN1; SMN2POLBMAPK1 | |
| SCHEMBL7806871 | 0.88 | ALDH1A1 (0.53) | METRPS6KA3SMN1; SMN2POLBMAPK1 | |
| SCHEMBL7807153 | 0.85 | MAPT (0.48) | METRPS6KA3SMN1; SMN2POLBMAPK1 | |
| SCHEMBL7807645 | 0.85 | ALDH1A1 (0.51) | METRPS6KA3SMN1; SMN2POLBMAPK1 | |
| SCHEMBL7815167 | 0.83 | ALDH1A1 (0.62) | METRPS6KA3SMN1; SMN2POLBMAPK1 | |
| SCHEMBL7806963 | 0.83 | SMN1; SMN2 (0.52) | METRPS6KA3SMN1; SMN2POLBMAPK1 | |
| SCHEMBL13685529 | 0.81 | KDM4E (0.55) | METRPS6KA3SMN1; SMN2POLBMAPK1 | |
| SCHEMBL3030632 | 0.80 | ALDH1A1 (0.65) | METRPS6KA3SMN1; SMN2POLBMAPK1 | |
| SCHEMBL4996885 | 0.79 | MET (0.49) | METRPS6KA3SMN1; SMN2POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |