Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818364 | 0.85 | CD274 (0.43) | LTA4HKCNH2HRH3MCHR1CD274 | |
| Oxalic Acid SCHEMBL6174230 | 0.81 | F2 (0.53) | LTA4HF2 | |
| Oxalic Acid SCHEMBL6174227 | 0.81 | F2 (0.53) | LTA4HF2 | |
| SCHEMBL7825326 | 0.79 | F2 (0.51) | MCHR1CD274F2 | |
| SCHEMBL7446083 | 0.76 | F2 (0.60) | LTA4HKCNH2HRH3CD274F2 | |
| SCHEMBL7809457 | 0.76 | F2 (0.41) | LTA4HCD274F2 | |
| SCHEMBL7820146 | 0.75 | CD274 (0.44) | KCNH2HRH3CD274F2 | |
| SCHEMBL7808978 | 0.74 | LTA4H (0.45) | LTA4HKCNH2HRH3TNF | |
| SCHEMBL7349591 | 0.74 | LTA4H (0.70) | LTA4HKCNH2HRH3 | |
| SCHEMBL7812445 | 0.72 | F2 (0.49) | CD274F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1027051-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |