Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 8/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PROC | P04070 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818365 | 0.82 | S1PR1 (0.45) | CD274F2HRH3KCNH2S1PR1 | |
| Oxalic Acid SCHEMBL6175630 | 0.81 | F2 (0.56) | F2 | |
| SCHEMBL7818611 | 0.81 | F2 (0.48) | F2HRH3KCNH2S1PR1 | |
| SCHEMBL7446083 | 0.79 | F2 (0.60) | CD274F2HRH3KCNH2 | |
| SCHEMBL7825326 | 0.77 | F2 (0.51) | CD274F2 | |
| SCHEMBL7817149 | 0.75 | LTA4H (0.51) | CD274F2HRH3KCNH2 | |
| SCHEMBL6172541 | 0.73 | F2 (0.57) | F2S1PR1 | |
| SCHEMBL6172781 | 0.72 | F2 (0.70) | F2 | |
| SCHEMBL7809457 | 0.71 | F2 (0.41) | CD274F2 | |
| SCHEMBL7439644 | 0.71 | F2 (0.60) | F2HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1027051-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |