Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814125 | 0.89 | ALDH1A1 (0.72) | ITGB3ITGA2BALDH1A1HTTKDM4E | |
| SCHEMBL7814082 | 0.89 | ITGB3 (0.65) | ITGB3ITGA2BALDH1A1HTTKDM4E | |
| SCHEMBL7811736 | 0.89 | ITGB3 (0.64) | ITGB3ITGA2BALDH1A1HTTKDM4E | |
| SCHEMBL7813301 | 0.88 | ALDH1A1 (0.64) | ITGB3ITGA2BALDH1A1HTTKDM4E | |
| SCHEMBL7810078 | 0.88 | ITGB3 (0.63) | ITGB3ITGA2BALDH1A1HTTKDM4E | |
| SCHEMBL7811714 | 0.88 | ITGB3 (0.63) | ITGB3ITGA2BALDH1A1HTTKDM4E | |
| SCHEMBL7810027 | 0.87 | MAPT (0.50) | ITGB3ITGA2BALDH1A1HTTKDM4E | |
| SCHEMBL7810083 | 0.87 | ALDH1A1 (0.69) | ITGB3ITGA2BALDH1A1HTTKDM4E | |
| SCHEMBL7817538 | 0.86 | PPARD (0.68) | ITGB3ITGA2BALDH1A1HTTKDM4E | |
| SCHEMBL7813621 | 0.81 | HSD11B1 (0.53) | ITGB3ITGA2BALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |