Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MPO | P05164 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818119 | 0.97 | HTR1A (0.65) | HTR1AMAPTMPOSLC6A4SMN1; SMN2 | |
| SCHEMBL7817707 | 0.88 | MAPT (0.68) | HTR1AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7825328 | 0.87 | HTR1A (0.66) | HTR1AMPOSLC6A4 | |
| SCHEMBL7824430 | 0.86 | HTR2A (0.57) | HTR1AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7817682 | 0.85 | MAPT (0.58) | HTR1AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7828214 | 0.85 | MAPT (0.70) | HTR1AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7824584 | 0.83 | MAPT (0.80) | HTR1AMAPTMPOSLC6A4 | |
| SCHEMBL7817700 | 0.83 | HTR2A (0.56) | HTR1AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6978453 | 0.82 | HTR1A (0.90) | HTR1AMPOSLC6A4 | |
| SCHEMBL6977070 | 0.82 | HTR1A (0.89) | HTR1AMPOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861248-B1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PROD (US) | 2001-12-12 | — | — | EP | claimed |
| CN-1074414-C | As 5-HT1AIndolylalkyl derivatives of benzodi * alkylmethylamines as receptor ligands | AMERICAN HOME PROUDCTS CORP (US) | 2001-11-07 | — | — | CN | claimed |
| CN-1205700-A | Indolylalkyl derivatives of benzodioxan methylamines as 5-HTiA receptor ligands | AMERICAN HOME PROD (US) | 1999-01-20 | — | — | CN | claimed |
| EP-0861248-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-09-02 | — | — | EP | claimed |
| WO-1997017343-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-05-15 | — | — | WO | claimed |
| EP-0861248-B1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PROD (US) | 2001-12-12 | — | — | EP | disclosed |
| CN-1074414-C | As 5-HT1AIndolylalkyl derivatives of benzodi * alkylmethylamines as receptor ligands | AMERICAN HOME PROUDCTS CORP (US) | 2001-11-07 | — | — | CN | disclosed |
| CN-1205700-A | Indolylalkyl derivatives of benzodioxan methylamines as 5-HTiA receptor ligands | AMERICAN HOME PROD (US) | 1999-01-20 | — | — | CN | disclosed |