SCHEMBL781789

SCHEMBL781789

CCN(O)CCNC(=O)C(N)=O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
GAA P10253 1/20 0.34
ALDH1A1 P00352 4/20 0.33
LMNA P02545 2/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.30
DNM1 Q05193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3634362 0.82 ALDH1A1 (0.49) KDM4EALDH1A1LMNASLC22A2SLC22A1
SCHEMBL16350995 0.77 KDM4E (0.46) KDM4EALDH1A1TSHRMAPK1BLM
SCHEMBL3760526 0.77 DNM1 (0.44) KDM4EGAAALDH1A1MAPK1CYP2C19
SCHEMBL29511205 0.74 ALDH1A1 (0.53) GAAALDH1A1LMNASLC22A2SLC22A1
SCHEMBL8395945 0.73
SCHEMBL31264254 0.72 GAA (0.45) KDM4EGAAALDH1A1LMNATSHR
SCHEMBL28969441 0.71 GAA (0.33) KDM4EGAAKMT2A
SCHEMBL28553543 0.70 MMP1 (0.41) KDM4EGAAALDH1A1LMNATSHR
SCHEMBL1264732 0.70 EPHX1 (0.52) GAAACHE
Dimethylamine SCHEMBL27569352 0.70 MMP1 (0.41) KDM4EGAAALDH1A1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5286267-A Antideposit agents TEXACO INC. (US) 1994-02-15 US claimed
EP-2272893-B1 Polymeric dispersants and non-aqueous dispersions AGFA GRAPHICS NV (BE) 2014-11-05 EP disclosed
US-8809419-B2 Polymeric dispersants and non-aqueous dispersions AGFA GRAPHICS NV (BE) 2014-08-19 US disclosed
US-20120071593-A1 POLYMERIC DISPERSANTS AND NON-AQUEOUS DISPERSIONS AGFA GRAPHICS NV (BE) 2012-03-22 US disclosed
EP-2272893-A1 Polymeric dispersants and non-aqueous dispersions Agfa Graphics N.V. (BE) 2011-01-12 EP disclosed
WO-2010145950-A1 POLYMERIC DISPERSANTS AND NON-AQUEOUS DISPERSIONS AGFA GRAPHICS NV (BE) 2010-12-23 WO disclosed
US-5286267-A Antideposit agents TEXACO INC. (US) 1994-02-15 US disclosed
US-5286267-A Antideposit agents TEXACO INC. (US) 1994-02-15 US disclosed
US-5286267-A Antideposit agents TEXACO INC. (US) 1994-02-15 US disclosed