SCHEMBL781801

SCHEMBL781801

[SiH3]Cc1cccc2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.58
CYP2C19 P33261 2/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2D6 P10635 2/20 0.54
TDP1 Q9NUW8 2/20 0.52
ACP3 P15309 1/20 0.50
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
CYP2A6 P11509 1/20 0.46
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HTT P42858 1/20 0.46
CA2 P00918 1/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
MTNR1A P48039 1/20 0.43
POLB P06746 1/20 0.43
CTNNB1 P35222 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25393878 0.87 HPRT1 (0.58) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL11650416 0.82 CYP1A2 (0.45) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL780469 0.81 CYP1A2 (0.54) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL3047898 0.79 CYP1A2 (0.62) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL599659 0.79 CYP2C19 (0.62) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL29490353 0.79 CYP2C19 (0.62) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
Hydrogen Sulfide SCHEMBL11348128 0.77 CYP2C19 (0.60) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL20916948 0.77 CYP1A2 (0.60) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL5352914 0.77 CYP1A2 (0.61) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL4667060 0.77 CYP2C19 (0.60) CYP1A2CYP2C19CYP2C9CYP2D6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874252-A Silomethylnaphthalene derivative and preparation method and application thereof 安徽师范大学 2022-08-09 CN claimed
EP-1971664-B1 EMITTING MATERIALS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2015-09-09 EP claimed
US-7919196-B2 Emitting materials and organic light emitting device using the same LG CHEM, LTD. (KR) 2011-04-05 US claimed
US-7604874-B2 Organic compounds for electroluminescence and organic electroluminescent devices using the same LG CHEM, LTD. (KR) 2009-10-20 US claimed
US-7485733-B2 Organic compounds for electroluminescence and organic electroluminescent devices using the same LG CHEM, LTD. (KR) 2009-02-03 US claimed
US-20090021149-A1 Emitting Materials and Organic Light Emitting Device Using the Same LG CHEM. LTD. (KR) 2009-01-22 US claimed
US-20070037012-A1 having an anthracene compound substituted with at least one thiophenyl ring; OLED organic light emitters; as displays with low power consumption, faster response time, higher brightness level, unlimited viewing angle LG CHEM, LTD. (KR) 2007-02-15 US claimed
EP-1501821-A1 NEW ORGANIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME LG Chem, Ltd. (KR) 2005-02-02 EP claimed
US-20040067387-A1 Organic compounds for electroluminescence and organic electroluminescent devices using the same LG CHEM. LTD. (KR) 2004-04-08 US claimed
WO-2003095445-A1 NEW ORGANIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME LG CHEM, LTD. (KR) 2003-11-20 WO claimed
CN-114874252-A Silomethylnaphthalene derivative and preparation method and application thereof 安徽师范大学 2022-08-09 CN disclosed
EP-2589643-B1 HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME SK CHEMICALS CO LTD (KR) 2017-09-20 EP disclosed
CN-103459434-B Hydrosilylation of vinyl macromers using metallocenes EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-05-11 CN disclosed
US-9278986-B2 Carbazole-based phosphine oxide compound, and organic electroluminescent device including the same SK CHEMICALS CO., LTD. (KR) 2016-03-08 US disclosed
US-9142784-B2 Highly efficient carbazole-based compound, and organic electroluminescence device comprising same SK CHEMICALS CO., LTD. (KR) 2015-09-22 US disclosed
EP-1501821-A1 NEW ORGANIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME LG Chem, Ltd. (KR) 2005-02-02 EP disclosed
US-6753401-B1 DEHYDROGENATIVE POLYMERIZATION OF QUINONE AND/OR DIOL WITH TRIHYDROSILANE OR DIHYDROSILANE IN PRESENCE OF PALLADIUM-CONTAINING CATALYST; POLYSILANES NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2004-06-22 US disclosed
US-20040067387-A1 Organic compounds for electroluminescence and organic electroluminescent devices using the same LG CHEM. LTD. (KR) 2004-04-08 US disclosed
WO-2003095445-A1 NEW ORGANIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME LG CHEM, LTD. (KR) 2003-11-20 WO disclosed
EP-1234829-A1 SILICON-CONTAINING POLYMERS National Institute of Advanced Industrial Science and Technology (JP) 2002-08-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090021149-A1 Emitting Materials and Organic Light Emitting Device Using the Same CRY1, CRY2, PER2 CYP1A2 1457/4885CYP2C19 1299/4885CYP2C9 1071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.