Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.42 |
| ▸ | KDM5A | P29375 | 10/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27376019 | 0.81 | CA12 (0.48) | KDM4CKDM5ACA12CA1CA9 | |
| SCHEMBL28420750 | 0.79 | CA12 (0.46) | KDM4CKDM5ACA12CA1CA9 | |
| SCHEMBL28383235 | 0.79 | CA12 (0.46) | KDM4CKDM5ACA12CA1CA9 | |
| SCHEMBL7743897 | 0.76 | CA12 (0.39) | KDM4CKDM5ACA12CA1CA9 | |
| SCHEMBL4183494 | 0.73 | GPR84 (0.44) | KDM4CKDM5ACA12CA1CA9 | |
| SCHEMBL27678347 | 0.73 | GPR84 (0.44) | KDM4CKDM5ACA12CA1CA9 | |
| SCHEMBL27678349 | 0.73 | GPR84 (0.44) | KDM4CKDM5ACA12CA1CA9 | |
| SCHEMBL12344488 | 0.73 | DNM1 (0.32) | KDM4CKDM5ACA12CA1CA9 | |
| SCHEMBL21729582 | 0.72 | CA12 (0.46) | CA12CA1 | |
| Bicarbonate SCHEMBL1259653 | 0.70 | DNM1 (0.57) | KDM4CKDM5ACA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124827-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | Dow AgroSciences LLC (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024739-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |