Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 2/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL781946 | 1.00 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2POLBHTT | |
| Sulfuric Acid SCHEMBL781947 | 0.94 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2POLBHTT | |
| Sulfuric Acid SCHEMBL781847 | 0.94 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2POLBHTT | |
| SCHEMBL30330931 | 0.93 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2POLBHTT | |
| SCHEMBL30330944 | 0.93 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2POLBHTT | |
| SCHEMBL29251697 | 0.93 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2POLBHTT | |
| SCHEMBL29251627 | 0.93 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2POLBHTT | |
| SCHEMBL30330038 | 0.93 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2POLBHTT | |
| SCHEMBL29251698 | 0.93 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2POLBHTT | |
| SCHEMBL29251623 | 0.93 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351728-B1 | PROCESS FOR PRODUCING AN AROMATIC ALDEHYDE COMPOUND | UBE INDUSTRIES (JP) | 2015-01-07 | — | — | EP | disclosed |
| US-8618335-B2 | Process for preparing aromatic aldehyde compound | UBE INDUSTRIES LTD. (JP) | 2013-12-31 | — | — | US | disclosed |
| US-20120071672-A1 | PROCESS FOR PREPARING AROMATIC ALDEHYDE COMPOUND | UBE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |
| EP-2351728-A1 | PROCESS FOR PRODUCING AN AROMATIC ALDEHYDE COMPOUND | Ube Industries, Ltd. (JP) | 2011-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071672-A1 | PROCESS FOR PREPARING AROMATIC ALDEHYDE COMPOUND | AOX1, ADH5, AOC2 | NPC1 4373/4885RAB9A 3631/4885SMN1; SMN2 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.