SCHEMBL781849

SCHEMBL781849

O=C(O)C(=Cc1ccccc1)CBr

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.63
CYP2C9 P11712 1/20 0.63
AKR1C3 P42330 1/20 0.55
RECQL P46063 1/20 0.52
AKR1C1 Q04828 1/20 0.48
HTT P42858 1/20 0.46
MME P08473 2/20 0.45
PTPN1 P18031 1/20 0.43
GSK3B P49841 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TP53 P04637 1/20 0.42
FBP1 P09467 1/20 0.41
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
OPRK1 P41145 1/20 0.40
GRIK1 P39086 1/20 0.40
HAO1 Q9UJM8 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4327979 1.00 CYP3A4 (0.63) CYP3A4CYP2C9AKR1C3RECQLAKR1C1
SCHEMBL8041928 1.00 CYP3A4 (0.63) CYP3A4CYP2C9AKR1C3RECQLAKR1C1
SCHEMBL8865069 0.89 TP53 (0.59) CYP3A4CYP2C9AKR1C3RECQLAKR1C1
SCHEMBL8865055 0.89 TP53 (0.59) CYP3A4CYP2C9AKR1C3RECQLAKR1C1
SCHEMBL8864851 0.84 CYP3A4 (0.47) CYP3A4CYP2C9AKR1C3HTTMEN1
SCHEMBL8864844 0.84 CYP3A4 (0.47) CYP3A4CYP2C9AKR1C3HTTMEN1
SCHEMBL2347233 0.84 CYP3A4 (0.50) CYP3A4CYP2C9AKR1C3RECQLAKR1C1
SCHEMBL8575022 0.84 CYP3A4 (0.59) CYP3A4CYP2C9AKR1C3RECQLAKR1C1
SCHEMBL7826083 0.84 CYP3A4 (0.47) CYP3A4CYP2C9AKR1C3RECQLAKR1C1
SCHEMBL7826086 0.84 CYP3A4 (0.47) CYP3A4CYP2C9AKR1C3RECQLAKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2517895-B1 ARTIFICIAL MARBLE HAVING TRANSPARENT AMORPHOUS PATTERN CHEIL IND INC (KR) 2016-02-17 EP claimed
EP-2049594-B1 METHOD OF PREPARING RESIN COMPOSITION FOR ARTIFICIAL MARBLE CHIP HAVING HIGH SPECIFIC GRAVITY AND HIGH INDEX OF REFRACTION CHEIL IND INC (KR) 2014-10-08 EP claimed
EP-2377896-B1 MARBLE CHIPS FOR AN ARTIFICIAL MARBLE, MANUFACTURING METHOD THEREOF, AND ARTIFICIAL MARBLE COMPRISING SAME CHEIL IND INC (KR) 2014-04-23 EP claimed
EP-2051951-B1 MARBLE CHIP, METHOD FOR PREPARING THE SAME AND ARTIFICIAL MARBLE USING THE SAME CHEIL IND INC (KR) 2012-09-05 EP claimed
US-20090087753-A1 VOLUME PHASE HOLOGRAM RECORDING MATERIAL, PRODUCTION PROCESS THEREFOR, AND RECORDED MATERIAL TOAGOSEI CO., LTD. (JP) 2009-04-02 US claimed
EP-0745621-B1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optical use ESSILOR INT (FR) 1998-04-15 EP claimed
EP-0745621-A1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optional use ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-12-04 EP claimed
EP-0242618-B1 Transparent optical article and process for preparing same NIPPON OILS & FATS CO LTD (JP) 1994-11-02 EP claimed
US-4065428-A Polymethylmethacrylate based molding compositions MONSANTO COMPANY (US) 1977-12-27 US claimed
WO-2020149384-A1 SEALING AGENT, CURED BODY, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE, AND METHOD FOR PRODUCING DEVICE デンカ株式会社 2020-07-23 WO disclosed
US-9677286-B2 Conductive flooring material and a production method therefor LG HAUSYS, LTD. (KR) 2017-06-13 US disclosed
US-9644078-B2 Release film and method for manufacturing the same LG HAUSYS, LTD. (KR) 2017-05-09 US disclosed
EP-1944656-B1 TONER FOR DEVELOPING ELECTROSTATIC IMAGES, TONER KITS, AND IMAGE FORMATION EQUIPMENT RICOH CO LTD (JP) 2016-05-04 EP disclosed
US-20160096910-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME ZEON CORPORATION (JP) 2016-04-07 US disclosed
US-5194438-A Plant safe fungicides BASF AKTIENGESELLSCHAFT (DE) 1993-03-16 US disclosed
US-5157037-A α-arylacrylates substituted by a heterocyclic radical, and fungicides which contain these compounds BASF AKTIENGESELLSCHAFT (DE) 1992-10-20 US disclosed
EP-0269821-B1 OPTICAL WAVEGUIDE HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-01 EP disclosed
EP-0269821-A1 Optical waveguide HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-08 EP disclosed
EP-0267459-A1 Transparent polymers HOECHST AKTIENGESELLSCHAFT (DE) 1988-05-18 EP disclosed
US-4704006-A HIGH REFRACTIVE INDEX, DYEABILITY, SOLVENT RESISTANCE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160096910-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME PCNA, TELO2, MSN CYP3A4 3118/4885CYP2C9 4218/4885AKR1C3 3277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.