Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18072401 | 0.81 | CES2 (0.35) | CES2LMNA | |
| SCHEMBL18726657 | 0.80 | CES2 (0.34) | CES2LMNA | |
| SCHEMBL9706627 | 0.77 | LMNA (0.47) | CES2LMNACYP3A4ALOX15MEN1 | |
| SCHEMBL855769 | 0.77 | — | — | |
| SCHEMBL18676186 | 0.74 | ESR2 (0.39) | CES2LMNACYP3A4 | |
| SCHEMBL17886581 | 0.74 | LMNA (0.34) | CES2LMNA | |
| SCHEMBL25457404 | 0.71 | ESR1 (0.30) | — | |
| SCHEMBL19445234 | 0.69 | LMNA (0.37) | CES2LMNACYP3A4ALOX15MEN1 | |
| SCHEMBL19226400 | 0.68 | CNR2 (0.36) | CES2LMNA | |
| SCHEMBL28099875 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802792-B2 | Partially hydrogenated bisphenol-A-based polymers as substitutes for bisphenol-A-based polymers | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2014-08-12 | — | — | US | disclosed |
| WO-2012036699-A1 | PARTIALLY HYDROGENATED BISPHENOL-A-BASED POLYMERS AS SUBSTITUTES FOR BISPHENOL-A-BASED POLYMERS | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| US-20120070593-A1 | PARTIALLY HYDROGENATED BISPHENOL-A-BASED POLYMERS AS SUBSTITUTES FOR BISPHENOL-A-BASED POLYMERS | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2012-03-22 | — | — | US | disclosed |