Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12519550 | 0.78 | LMNA (0.38) | LMNACES2 | |
| SCHEMBL781856 | 0.77 | CES2 (0.37) | LMNACES2CYP3A4ALOX15MEN1 | |
| SCHEMBL18676186 | 0.76 | ESR2 (0.39) | LMNACES2CYP3A4ALDH1A1 | |
| SCHEMBL31545085 | 0.76 | LMNA (0.70) | LMNACES2CYP3A4ALOX15MEN1 | |
| SCHEMBL18072401 | 0.74 | CES2 (0.35) | LMNACES2 | |
| SCHEMBL6435607 | 0.74 | LMNA (0.42) | LMNACES2CYP3A4ALOX15MEN1 | |
| SCHEMBL13782375 | 0.74 | LMNA (0.42) | LMNACES2CYP3A4ALOX15MEN1 | |
| SCHEMBL5698477 | 0.74 | LMNA (0.42) | LMNACES2CYP3A4ALOX15MEN1 | |
| SCHEMBL4402841 | 0.74 | LMNA (0.42) | LMNACES2CYP3A4ALOX15MEN1 | |
| SCHEMBL4440899 | 0.74 | LMNA (0.42) | LMNACES2CYP3A4ALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012983-A1 | A METHOD OF FLUORINATING BY USING N-FLUOROPYRIDINIUM PYRIDINE HEPTAFLUORODIBORATE | ALLIED-SIGNAL INC. (US) | 1992-08-06 | — | — | WO | disclosed |