Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.39 |
| ▸ | NQO1 | P15559 | 2/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818284 | 0.93 | NQO2 (0.38) | NQO2NQO1KAT2BCYP19A1CNR2 | |
| SCHEMBL7821158 | 0.88 | TOP2A (0.35) | NQO2NQO1CYP19A1CNR2BCHE | |
| SCHEMBL7809943 | 0.83 | CNR2 (0.33) | CNR2BCHEACHE | |
| SCHEMBL7817393 | 0.81 | KDM4E (0.35) | NQO2NQO1CYP19A1RAD52MEN1 | |
| SCHEMBL7817848 | 0.80 | TOP2A (0.40) | NQO1CNR2BCHEACHE | |
| SCHEMBL7808985 | 0.79 | TOP2A (0.40) | NQO2NQO1KAT2BSMARCA2KEAP1 | |
| SCHEMBL7804639 | 0.75 | ECE1 (0.40) | NQO2NQO1KAT2BATMEHMT2 | |
| SCHEMBL7805085 | 0.75 | ECE1 (0.40) | KAT2BEHMT2 | |
| SCHEMBL9389199 | 0.75 | TOP2A (0.40) | CYP19A1MEN1KMT2AEHMT2 | |
| SCHEMBL7809049 | 0.74 | EHMT2 (0.39) | NQO2NQO1KAT2BEHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750619-B1 | HETERO-ANNULATED INDAZOLES | NOVUSPHARMA SPA (IT) | 2001-05-30 | — | — | EP | disclosed |
| US-5596097-A | ANTITUMOR AGENTS | THE UNIVERSITY OF VERMONT (US) | 1997-01-21 | — | — | US | disclosed |
| WO-1995024407-A1 | HETERO-ANNULATED INDAZOLES | BOEHRINGER MANNHEIM ITALIA, S.P.A. (IT) | 1995-09-14 | — | — | WO | disclosed |