Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819967 | 1.00 | ALDH1A1 (0.49) | ALDH1A1BRD4L3MBTL1FFAR1PPARG | |
| SCHEMBL7822408 | 0.87 | ALDH1A1 (0.65) | ALDH1A1BRD4L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL7822412 | 0.87 | ALDH1A1 (0.65) | ALDH1A1BRD4L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL27543049 | 0.82 | ALDH1A1 (0.70) | ALDH1A1BRD4L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL7822763 | 0.79 | ALDH1A1 (0.42) | ALDH1A1BRD4FFAR1PPARGNPC1 | |
| SCHEMBL7823773 | 0.78 | ALDH1A1 (0.59) | ALDH1A1BRD4L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL7822118 | 0.77 | MEN1 (0.64) | ALDH1A1BRD4L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL7822120 | 0.77 | MEN1 (0.64) | ALDH1A1BRD4L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL10734451 | 0.76 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL10734447 | 0.76 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |