Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820384 | 0.85 | POLB (0.67) | ALDH1A1MAPTKDM4ETSHRPOLB | |
| SCHEMBL5789989 | 0.83 | MAPT (0.58) | ALDH1A1MAPTKDM4EL3MBTL1TSHR | |
| SCHEMBL7204676 | 0.83 | ALDH1A1 (0.77) | ALDH1A1MAPTKDM4EL3MBTL1TSHR | |
| SCHEMBL7804821 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EL3MBTL1TSHR | |
| SCHEMBL13997417 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MAPTKDM4EL3MBTL1TSHR | |
| SCHEMBL31433349 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EL3MBTL1TSHR | |
| SCHEMBL30989179 | 0.79 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4EL3MBTL1TSHR | |
| SCHEMBL1143451 | 0.79 | POLB (0.72) | ALDH1A1MAPTKDM4EL3MBTL1TSHR | |
| SCHEMBL31588120 | 0.79 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4EL3MBTL1TSHR | |
| SCHEMBL30414489 | 0.79 | POLB (0.72) | ALDH1A1MAPTKDM4EL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655996-B1 | SUBSTITUTED BENZYLAMINO NITROGEN CONTAINING NON-AROMATIC HETEROCYCLES | PFIZER (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-1114823-A2 | Substituted benzylamino nitrogen containing non-aromatic heterocycles | PFIZER INC. (US) | 2001-07-11 | — | — | EP | disclosed |
| US-5721255-A | Substituted benzylamino nitrogen containing non-aromatic heterocycles | PFIZER INC. (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0655996-A1 | SUBSTITUTED BENZYLAMINO NITROGEN CONTAINING NON-AROMATIC HETEROCYCLES | PFIZER INC. (US) | 1995-06-07 | — | — | EP | disclosed |
| WO-1994004496-A9 | SUBSTITUTED BENZYLAMINO NITROGEN CONTAINING NON-AROMATIC HETEROCYCLES | — | 1995-01-26 | — | — | WO | disclosed |
| WO-1994004496-A1 | SUBSTITUTED BENZYLAMINO NITROGEN CONTAINING NON-AROMATIC HETEROCYCLES | PFIZER INC. (US) | 1994-03-03 | — | — | WO | disclosed |