Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.55 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | EEF2K | O00418 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684799 | 0.89 | RIPK1 (0.54) | RIPK1CYP26A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL19435047 | 0.86 | RIPK1 (0.76) | RIPK1CYP26A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL7813724 | 0.86 | CYP26A1 (0.56) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL19435046 | 0.86 | RIPK1 (0.76) | RIPK1CYP26A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL8558646 | 0.86 | RIPK1 (0.55) | RIPK1CYP26A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL12666568 | 0.85 | RIPK1 (0.74) | RIPK1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12666549 | 0.85 | RIPK1 (0.60) | RIPK1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25587388 | 0.85 | RIPK1 (0.74) | RIPK1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25587390 | 0.85 | RIPK1 (0.74) | RIPK1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8062915 | 0.83 | ALDH1A1 (0.56) | RIPK1CYP26A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |