Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CASP1 | P29466 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275798 | 0.86 | KDM4E (0.58) | KDM4ENPSR1ALDH1A1MAPTMEN1 | |
| SCHEMBL13295969 | 0.79 | ALDH1A1 (0.49) | KDM4ENPSR1ALDH1A1MAPTMEN1 | |
| SCHEMBL6441000 | 0.75 | KMT2A (0.55) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3324580 | 0.74 | ALDH1A1 (0.45) | KDM4ENPSR1ALDH1A1MAPTMEN1 | |
| SCHEMBL7817348 | 0.72 | MET (0.59) | KDM4ENPSR1ALDH1A1MAPTMEN1 | |
| SCHEMBL7815153 | 0.72 | KDM4E (0.60) | KDM4ENPSR1ALDH1A1MAPTMEN1 | |
| SCHEMBL7817108 | 0.70 | KDM4E (0.77) | KDM4ENPSR1ALDH1A1MAPTMEN1 | |
| SCHEMBL27372710 | 0.70 | KDM4E (0.77) | KDM4ENPSR1ALDH1A1MAPTMEN1 | |
| SCHEMBL7820657 | 0.68 | KDM4E (0.61) | KDM4ENPSR1ALDH1A1MAPTMEN1 | |
| SCHEMBL13856692 | 0.67 | MAPT (1.00) | KDM4ENPSR1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |