SCHEMBL7821029

SCHEMBL7821029

Cn1c(C(F)(F)F)cc(=O)n(-c2cc(NS(=O)(=O)CCCCl)c(Cl)cc2F)c1=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRAF P15056 3/20 0.30
PPOX P50336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8762906 0.90 BRAF (0.36) BRAF
SCHEMBL7833797 0.89 PSIP1 (0.33) BRAFPPOX
SCHEMBL5361878 0.85 PPOX (0.40) PPOX
SCHEMBL8461514 0.82 PPOX (0.32) PPOX
SCHEMBL9679435 0.81 PPOX (0.35) PPOX
SCHEMBL27692746 0.80 PPOX (0.31) PPOX
SCHEMBL7951096 0.79 BRD9 (0.31)
SCHEMBL8707853 0.79 KMT2A (0.32)
SCHEMBL8696878 0.79
SCHEMBL8697370 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563384-B1 URACIL DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2001-10-04 EP disclosed
US-5356863-A Herbicides NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1994-10-18 US disclosed
EP-0563384-A1 URACIL DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1993-10-06 EP disclosed