SCHEMBL7821115

SCHEMBL7821115

O=C(O)C(CCCCOCc1ccccc1)(CCCCOCc1ccccc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.48
TSHR P16473 1/20 0.45
EPHX2 P34913 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
TEAD3 Q99594 1/20 0.44
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19065970 0.85 L3MBTL1 (0.47) L3MBTL1TSHREPHX2TDP1TEAD3
SCHEMBL9514922 0.85 TSHR (0.47) L3MBTL1TSHRTDP1HTTSMN1; SMN2
SCHEMBL29439954 0.84 L3MBTL1 (0.46) L3MBTL1TSHREPHX2TDP1TEAD3
SCHEMBL17746747 0.84 PPARA (0.52) L3MBTL1TDP1
SCHEMBL29033242 0.83 L3MBTL1 (0.54) L3MBTL1EPHX2TDP1
SCHEMBL30533272 0.83 L3MBTL1 (0.54) L3MBTL1EPHX2TDP1
SCHEMBL10782004 0.83 L3MBTL1 (0.54) L3MBTL1EPHX2TDP1
SCHEMBL30533275 0.83 L3MBTL1 (0.54) L3MBTL1EPHX2TDP1
SCHEMBL21677644 0.83 L3MBTL1 (0.54) L3MBTL1EPHX2TDP1
SCHEMBL10864410 0.83 L3MBTL1 (0.45) L3MBTL1TSHREPHX2TDP1TEAD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160058682-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT OREAL (FR) 2016-03-03 US disclosed
US-9162976-B2 Composition containing a dibenzoylmethane screening agent and a hydrophilic or water-soluble merocyanin uv-screening agent; process for photostabilizing the dibenzoylmethane screening agent L'OREAL (FR) 2015-10-20 US disclosed
US-20130058990-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT L'OREAL (FR) 2013-03-07 US disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160058682-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT CRYZ, MSH6, TYR L3MBTL1 4616/4885TSHR 4054/4885EPHX2 315/4885
US-20130058990-A1 COMPOSITION CONTAINING A DIBENZOYLMETHANE SCREENING AGENT AND A HYDROPHILIC OR WATER-SOLUBLE MEROCYANIN UV-SCREENING AGENT; PROCESS FOR PHOTOSTABILIZING THE DIBENZOYLMETHANE SCREENING AGENT CRYZ, MSH6, TYR L3MBTL1 4623/4885TSHR 4160/4885EPHX2 364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.