Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826009 | 0.95 | LMNA (0.60) | LMNAHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL7403811 | 0.88 | NR4A2 (0.62) | LMNAHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL30666330 | 0.88 | NR4A2 (0.62) | LMNAHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL3844203 | 0.87 | HSD17B3 (0.56) | LMNAL3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL17952793 | 0.87 | HSD17B3 (0.56) | LMNAL3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL13472220 | 0.85 | L3MBTL1 (0.50) | LMNAHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL16203113 | 0.84 | TDP1 (0.61) | LMNAHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL3604586 | 0.83 | PARP1 (0.49) | LMNAHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL3896481 | 0.83 | OGG1 (0.58) | LMNAL3MBTL1MAPTPARP1ALDH1A1 | |
| SCHEMBL13472221 | 0.81 | SIRT2 (0.55) | LMNAL3MBTL1MAPTTDP1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |