SCHEMBL7821671

SCHEMBL7821671

O=[N+]([O-])OCC1C[CH]CCC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7810422 0.91 ALDH1A1 (0.32) MMP2MMP9
SCHEMBL7817737 0.81 MMP2 (0.35) MMP2MMP9
SCHEMBL7818099 0.81
SCHEMBL8957450 0.78
SCHEMBL8957322 0.77 CCNA2 (0.41) MMP2MMP9
SCHEMBL23829716 0.74
SCHEMBL9875012 0.74 ALDH1A1 (0.40) MMP2MMP9
SCHEMBL6438537 0.74 ALDH1A1 (0.40) MMP2MMP9
SCHEMBL7809279 0.73 MMP2 (0.34) MMP2MMP9
SCHEMBL6135357 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0798298-B1 THIAZOLIDINONE OR OXAZOLIDINONE DERIVATIVES TO TREAT ANGINA PECTORIS OR COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENT SANKYO CO (JP) 2001-08-08 EP disclosed
US-5843973-A Thiazolidinone compounds and composition for angina pectoris comprising the compounds as an active ingredient SANKYO COMPANY, LIMITED (JP) 1998-12-01 US disclosed
EP-0798298-A1 THIAZOLIDINONE COMPOUNDS OR ANGINA PECTORIS REMEDY OR PREVENTIVE CONTAINING THE SAME AS ACTIVE INGREDIENT SANKYO COMPANY LIMITED (JP) 1997-10-01 EP disclosed