Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821739 | 1.00 | CES2 (0.54) | CES2CES1MAOBPARP1ABCG2 | |
| SCHEMBL10399231 | 0.87 | CES2 (0.56) | CES2CES1MAOBPARP1ABCG2 | |
| SCHEMBL10399232 | 0.87 | CES2 (0.56) | CES2CES1MAOBPARP1ABCG2 | |
| SCHEMBL10399324 | 0.87 | CES2 (0.56) | CES2CES1MAOBPARP1ABCG2 | |
| SCHEMBL10398652 | 0.84 | MTNR1A (0.55) | CES2CES1MAOBPARP1ABCG2 | |
| SCHEMBL10398653 | 0.84 | MTNR1A (0.55) | CES2CES1MAOBPARP1ABCG2 | |
| SCHEMBL10398651 | 0.84 | MTNR1A (0.55) | CES2CES1MAOBPARP1ABCG2 | |
| SCHEMBL10398346 | 0.81 | THRB (0.53) | CES2CES1MAOBPARP1ALDH1A1 | |
| SCHEMBL4008579 | 0.81 | CES2 (0.61) | CES2CES1MAOBPARP1ABCG2 | |
| SCHEMBL10398345 | 0.81 | THRB (0.53) | CES2CES1MAOBPARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |