Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 6/20 | 0.65 |
| ▸ | CA1 | P00915 | 5/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821757 | 1.00 | LMNA (0.67) | LMNASMN1; SMN2CA2CA1CA12 | |
| SCHEMBL9404117 | 0.85 | EGFR (0.71) | CA2CA1KMT2AMEN1MAOB | |
| SCHEMBL20334064 | 0.85 | EGFR (0.71) | CA2CA1KMT2AMEN1MAOB | |
| SCHEMBL30342737 | 0.85 | LMNA (0.55) | LMNASMN1; SMN2CA2CA1CA12 | |
| SCHEMBL15600629 | 0.83 | CA1 (0.73) | LMNASMN1; SMN2CA2CA1CA12 | |
| SCHEMBL12416679 | 0.83 | SMN1; SMN2 (0.71) | LMNASMN1; SMN2CA2CA1CA12 | |
| SCHEMBL14103565 | 0.83 | SMN1; SMN2 (0.77) | LMNASMN1; SMN2CA2CA1CA12 | |
| SCHEMBL10637987 | 0.82 | ALDH1A1 (0.67) | LMNASMN1; SMN2CA2CA1CA12 | |
| SCHEMBL10637996 | 0.82 | ALDH1A1 (0.67) | LMNASMN1; SMN2CA2CA1CA12 | |
| SCHEMBL1527094 | 0.80 | SMN1; SMN2 (0.72) | LMNASMN1; SMN2CA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |