Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821775 | 1.00 | PIM1 (0.53) | PIM1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL11887710 | 0.90 | PTGS1 (0.54) | PIM1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL1720334 | 0.82 | CA2 (0.54) | MAPTALDH1A1POLBCYP1A2KDM4E | |
| SCHEMBL12416716 | 0.82 | NPC1 (0.67) | NPC1RAB9AMAPTALDH1A1POLB | |
| SCHEMBL7827465 | 0.78 | CA2 (0.62) | MAPTALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL7827463 | 0.78 | CA2 (0.62) | MAPTALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL7823200 | 0.76 | CA2 (0.49) | ALDH1A1SMN1; SMN2LMNAPTGS1PTGS2 | |
| SCHEMBL7823202 | 0.76 | CA2 (0.49) | ALDH1A1SMN1; SMN2LMNAPTGS1PTGS2 | |
| SCHEMBL12416591 | 0.75 | CYP1A2 (0.61) | NPC1RAB9AMAPTALDH1A1POLB | |
| SCHEMBL16274602 | 0.75 | CYP1A2 (0.61) | NPC1RAB9AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |