Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827463 | 1.00 | CA2 (0.62) | CA2EGFRLCKCA1ALDH1A1 | |
| SCHEMBL1720334 | 0.95 | CA2 (0.54) | CA2EGFRLCKCA1ALDH1A1 | |
| SCHEMBL7823202 | 0.88 | CA2 (0.49) | CA2EGFRLCKCA1ALDH1A1 | |
| SCHEMBL7823200 | 0.88 | CA2 (0.49) | CA2EGFRLCKCA1ALDH1A1 | |
| SCHEMBL7829422 | 0.84 | ALDH1A1 (0.58) | CA2CA1ALDH1A1CA12CA9 | |
| SCHEMBL7829424 | 0.84 | ALDH1A1 (0.58) | CA2CA1ALDH1A1CA12CA9 | |
| SCHEMBL7814593 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRMEN1MAPTBLM | |
| SCHEMBL7814591 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRMEN1MAPTBLM | |
| SCHEMBL22502063 | 0.80 | ALDH1A1 (0.53) | CA2EGFRLCKCA1ALDH1A1 | |
| SCHEMBL7821775 | 0.78 | PIM1 (0.53) | ALDH1A1MEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |