Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MMP16 | P51512 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30222272 | 0.86 | PTGS2 (0.46) | PTGS2CXCL8MMP1MMP2MMP9 | |
| SCHEMBL5983552 | 0.86 | PTGS2 (0.46) | PTGS2CXCL8MMP1MMP2MMP9 | |
| SCHEMBL5112475 | 0.86 | PTGS2 (0.46) | PTGS2CXCL8MMP1MMP2MMP9 | |
| SCHEMBL1063487 | 0.85 | PTGS2 (0.44) | PTGS2CXCL8MMP1MMP2MMP9 | |
| SCHEMBL6916097 | 0.84 | GABRA1 (0.48) | PTGS2CXCL8MMP1MMP2MMP9 | |
| SCHEMBL9119656 | 0.83 | PTGS2 (0.49) | PTGS2CXCL8MMP1MMP2MMP9 | |
| SCHEMBL1394339 | 0.83 | PTGS2 (0.49) | PTGS2CXCL8MMP1MMP2MMP9 | |
| SCHEMBL3026634 | 0.83 | PTGS2 (0.43) | PTGS2CXCL8MMP1MMP2MMP9 | |
| SCHEMBL3155111 | 0.83 | PTGS2 (0.49) | PTGS2CXCL8MMP1MMP2MMP9 | |
| SCHEMBL11669660 | 0.83 | AKR1B1 (0.52) | PTGS2CXCL8MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11315064-A | — | — | None | — | — | JP | disclosed |
| CN-100383121-C | Substituted benzyl ester and its preparation process and novel process for preparing substituted mopipe therefrom | TIANJIN TAIPU PHARMACEUTICAL S (CN) | 2008-04-23 | — | — | CN | disclosed |
| CN-1827598-A | Substituted benzyl ester and its preparation process and novel process for preparing substituted mopipe therefrom | TIANJIN TAIPU PHARMACEUTICAL S (CN) | 2006-09-06 | — | — | CN | disclosed |
| EP-1091938-A2 | ANTIHISTAMINIC PIPERIDINE DERIVATIVES AND INTERMEDIATES FOR THE PREPARATION THEREOF | Aventis Pharmaceuticals Inc. (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001671-A2 | ANTIHISTAMINIC PIPERIDINE DERIVATIVES AND INTERMEDIATES FOR THE PREPARATION THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2000-01-13 | — | — | WO | disclosed |
| JP-H11315064-A | PRODUCTION OF OPTICALLY ACTIVE PHENYLPROPIONIC ACID DERIVATIVE | AJINOMOTO CO INC | 1999-11-16 | — | — | JP | disclosed |