Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30371912 | 0.75 | CYP2C19 (0.61) | CYP2C19TBXAS1SMN1; SMN2POLBCYP2D6 | |
| SCHEMBL19228532 | 0.72 | CYP2C19 (0.53) | CYP2C19TBXAS1SMN1; SMN2POLBCYP2D6 | |
| SCHEMBL643461 | 0.72 | CYP2C19 (0.53) | CYP2C19TBXAS1SMN1; SMN2POLBCYP2D6 | |
| SCHEMBL29757088 | 0.72 | LMNA (0.59) | CYP2C19SMN1; SMN2POLBCYP2D6LMNA | |
| SCHEMBL65737 | 0.72 | LMNA (0.59) | CYP2C19SMN1; SMN2POLBCYP2D6LMNA | |
| SCHEMBL20769804 | 0.72 | LMNA (0.59) | CYP2C19SMN1; SMN2POLBCYP2D6LMNA | |
| SCHEMBL1715 | 0.72 | LMNA (0.59) | CYP2C19SMN1; SMN2POLBCYP2D6LMNA | |
| SCHEMBL67237 | 0.72 | LMNA (0.59) | CYP2C19SMN1; SMN2POLBCYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL16401889 | 0.71 | CYP2C19 (0.52) | CYP2C19TBXAS1SMN1; SMN2POLBCYP2D6 | |
| SCHEMBL1716620 | 0.71 | POLB (0.53) | CYP2C19TBXAS1SMN1; SMN2POLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500864-B1 | ANTIMUSCARINIC BRONCHODILATORS | PFIZER LTD (GB) | 2001-09-19 | — | — | EP | disclosed |