Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317736 | 0.83 | NPSR1 (0.49) | RAB9AKMT2ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL7832442 | 0.82 | RAB9A (0.47) | RAB9AKMT2ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL7824638 | 0.82 | RAB9A (0.47) | RAB9AKMT2ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL7838459 | 0.81 | RAB9A (0.46) | RAB9AKMT2ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL7823161 | 0.81 | RAB9A (0.47) | RAB9AKMT2ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL7832142 | 0.78 | RAB9A (0.47) | RAB9AKMT2ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL7824065 | 0.77 | KMT2A (0.48) | RAB9AKMT2ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL7832879 | 0.76 | ALOX5 (0.54) | RAB9AKMT2ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL7835009 | 0.75 | TSHR (0.47) | RAB9AKMT2ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL7825727 | 0.74 | TSHR (0.43) | RAB9AKMT2ANPC1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1344270-A | Functionalized heterocycles as chemokine receptor modulators | THOUSAND YEARS MEDICAMENTS INC (US) | 2002-04-10 | — | — | CN | disclosed |
| EP-1144415-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000042045-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | disclosed |