Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.36 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | BCR | P11274 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7163241 | 0.99 | AURKA (0.36) | AURKAAURKBTRPC3TRPC6GRM5 | |
| SCHEMBL7858511 | 0.89 | AURKA (0.36) | AURKAAURKBKDM4EABL1BCR | |
| SCHEMBL6160285 | 0.89 | AURKA (0.36) | AURKAAURKBABL1BCRBTK | |
| Revaprazan SCHEMBL6990999 | 0.89 | MEN1 (0.40) | TRPC3TRPC6KDM4EMAPTLMNA | |
| Revaprazan SCHEMBL29388090 | 0.89 | MEN1 (0.40) | TRPC3TRPC6KDM4EMAPTLMNA | |
| Revaprazan SCHEMBL6993033 | 0.89 | MEN1 (0.40) | TRPC3TRPC6KDM4EMAPTLMNA | |
| Revaprazan SCHEMBL2194461 | 0.89 | MEN1 (0.40) | TRPC3TRPC6KDM4EMAPTLMNA | |
| Hydrochloric Acid SCHEMBL7164212 | 0.89 | AURKA (0.35) | AURKAAURKBKDM4EABL1BCR | |
| SCHEMBL7832318 | 0.89 | AURKA (0.35) | AURKAAURKBABL1BCRBTK | |
| Hydrochloric Acid SCHEMBL6158829 | 0.89 | AURKA (0.35) | AURKAAURKBKDM4EABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |