Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | BCR | P11274 | 2/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6159247 | 0.99 | AURKA (0.35) | AURKAAURKBAPPBRD4AXL | |
| SCHEMBL6158502 | 0.91 | KMT2A (0.37) | AURKAAURKBAPPBRD4ADRA2A | |
| SCHEMBL7858511 | 0.91 | AURKA (0.36) | AURKAAURKBAPPAXLABL1 | |
| Hydrochloric Acid SCHEMBL6160343 | 0.91 | KMT2A (0.36) | AURKAAURKBAPPBRD4ADRA2A | |
| Hydrochloric Acid SCHEMBL6158829 | 0.91 | AURKA (0.35) | AURKAAURKBAPPAXLABL1 | |
| SCHEMBL7822656 | 0.89 | AURKA (0.36) | AURKAAURKBAPPABL1BCR | |
| Hydrochloric Acid SCHEMBL7163241 | 0.88 | AURKA (0.36) | AURKAAURKBAPPABL1BCR | |
| SCHEMBL7835940 | 0.88 | MEN1 (0.35) | AURKAAURKBAPPBRD4ADRA2A | |
| SCHEMBL7823470 | 0.87 | DRD2 (0.35) | BRD4ADRA2AADRA2BADRA2CDRD2 | |
| Hydrochloric Acid SCHEMBL6159808 | 0.87 | MEN1 (0.34) | AURKAAURKBAPPBRD4ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |