Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 11/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843574 | 0.89 | LMNA (0.42) | LMNAHPGDSMN1; SMN2MAPTHTT | |
| SCHEMBL7832002 | 0.87 | TLR7 (0.33) | — | |
| SCHEMBL7832293 | 0.84 | LMNA (0.43) | LMNAHPGDSMN1; SMN2MAPTHTT | |
| Hydrochloric Acid SCHEMBL8122175 | 0.79 | MAPT (0.42) | LMNAHPGDSMN1; SMN2MAPTHTT | |
| SCHEMBL14423952 | 0.79 | EGFR (0.47) | LMNAHPGDSMN1; SMN2MAPTHTT | |
| SCHEMBL7832974 | 0.75 | TLR8 (0.39) | — | |
| SCHEMBL7840427 | 0.73 | LMNA (0.43) | LMNAHPGDSMN1; SMN2MAPTHTT | |
| SCHEMBL29809123 | 0.72 | ATM (0.46) | LMNAHPGDMAPTALDH1A1KMT2A | |
| SCHEMBL29121426 | 0.72 | ATM (0.46) | LMNAHPGDMAPTALDH1A1KMT2A | |
| SCHEMBL7823333 | 0.70 | ESR1 (0.38) | MAPTL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681570-B1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING & MFG (US) | 2001-03-14 | — | — | EP | claimed |
| EP-0681570-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-11-15 | — | — | EP | claimed |
| WO-1994017043-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-08-04 | — | — | WO | claimed |
| EP-0681570-B1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING & MFG (US) | 2001-03-14 | — | — | EP | disclosed |
| EP-0681570-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-11-15 | — | — | EP | disclosed |
| WO-1994017043-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-08-04 | — | — | WO | disclosed |