Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832002 | 0.88 | TLR7 (0.33) | TLR8DHFRTLR7 | |
| SCHEMBL7843574 | 0.84 | LMNA (0.42) | TLR8 | |
| SCHEMBL7823367 | 0.75 | LMNA (0.41) | — | |
| SCHEMBL9427790 | 0.73 | DHFR (0.48) | TLR8DHFRDCPS | |
| SCHEMBL24604516 | 0.72 | TLR7 (0.43) | TLR8TLR7APP | |
| SCHEMBL7837867 | 0.70 | TLR7 (0.67) | TLR8DHFRTLR7 | |
| SCHEMBL7823333 | 0.69 | ESR1 (0.38) | TLR8TLR7 | |
| SCHEMBL8127516 | 0.69 | ACHE (0.32) | — | |
| Hydrochloric Acid SCHEMBL7834755 | 0.68 | ESR1 (0.38) | TLR8TLR7 | |
| SCHEMBL30779218 | 0.68 | ALDH1A1 (0.49) | DHFRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681570-B1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING & MFG (US) | 2001-03-14 | — | — | EP | claimed |