Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832974 | 0.88 | TLR8 (0.39) | TLR7TLR8DHFR | |
| SCHEMBL7823367 | 0.87 | LMNA (0.41) | — | |
| SCHEMBL7823333 | 0.82 | ESR1 (0.38) | TLR7TLR8 | |
| Hydrochloric Acid SCHEMBL7834755 | 0.81 | ESR1 (0.38) | TLR7TLR8 | |
| Hydrochloric Acid SCHEMBL8121167 | 0.78 | DHFR (0.38) | TLR8DHFR | |
| SCHEMBL7843574 | 0.75 | LMNA (0.42) | TLR8 | |
| SCHEMBL9273378 | 0.72 | TLR7 (0.62) | TLR7TLR8 | |
| SCHEMBL3639875 | 0.70 | DHFR (0.55) | DHFR | |
| SCHEMBL7832293 | 0.70 | LMNA (0.43) | — | |
| SCHEMBL29809256 | 0.69 | ALDH1A1 (0.55) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681570-B1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING & MFG (US) | 2001-03-14 | — | — | EP | claimed |
| EP-0681570-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-11-15 | — | — | EP | claimed |
| WO-1994017043-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-08-04 | — | — | WO | claimed |
| EP-0681570-B1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING & MFG (US) | 2001-03-14 | — | — | EP | disclosed |
| EP-0681570-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-11-15 | — | — | EP | disclosed |
| WO-1994017043-A1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-08-04 | — | — | WO | disclosed |