Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7823591 | 1.00 | MAPT (0.69) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8100698 | 0.84 | PLA2G4A (0.57) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL3928064 | 0.83 | MAPT (0.74) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7813059 | 0.81 | MEN1 (0.67) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7813056 | 0.81 | MEN1 (0.67) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6829500 | 0.79 | LMNA (0.64) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6829496 | 0.79 | LMNA (0.64) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3845633 | 0.76 | MEN1 (0.67) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL2411839 | 0.76 | ALDH1A1 (0.66) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL10415000 | 0.76 | ALDH1A1 (0.66) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |