Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28745633 | 0.88 | MAPT (0.70) | MAPTALDH1A1MEN1PKMKMT2A | |
| SCHEMBL7823365 | 0.85 | MAPT (0.77) | MAPTALDH1A1MEN1PKMKMT2A | |
| SCHEMBL6129750 | 0.84 | CRHBP (0.57) | MAPTALDH1A1MAPK1HTTGAA | |
| SCHEMBL21626406 | 0.84 | CRHBP (0.57) | MAPTALDH1A1MAPK1HTTGAA | |
| SCHEMBL6129749 | 0.84 | CRHBP (0.57) | MAPTALDH1A1MAPK1HTTGAA | |
| SCHEMBL7064305 | 0.81 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1PKMKMT2A | |
| SCHEMBL124856 | 0.81 | MAPT (0.70) | MAPTALDH1A1MEN1PKMKMT2A | |
| SCHEMBL115470 | 0.81 | MAPT (0.70) | MAPTALDH1A1MEN1PKMKMT2A | |
| SCHEMBL7455626 | 0.80 | MAPT (0.66) | MAPTALDH1A1MEN1PKMKMT2A | |
| SCHEMBL31551021 | 0.80 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |