Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5461147 | 0.89 | MAPT (0.67) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL115470 | 0.88 | MAPT (0.70) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL7823365 | 0.85 | MAPT (0.77) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL7455626 | 0.85 | MAPT (0.66) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL7350226 | 0.84 | MAPT (0.65) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL9030307 | 0.83 | MAPT (0.64) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL116464 | 0.83 | MAPT (0.64) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL8340872 | 0.82 | MAPT (0.62) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL7355650 | 0.82 | MAPT (0.62) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL7823671 | 0.81 | MAPT (0.71) | MAPTALDH1A1MAPK1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 470 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2158942-A2 | Direct hair dye composition comprising insoluble oxygenated compounds and processes | L'Oreal (FR) | 2010-03-03 | — | — | EP | claimed |
| US-7651534-B2 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL SA (FR) | 2010-01-26 | — | — | US | claimed |
| EP-1757326-B1 | Direct dying composition comprising insoluble oxygenated compounds and processes | OREAL (FR) | 2009-01-07 | — | — | EP | claimed |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | claimed |
| EP-1757326-A1 | Direct dying composition comprising insoluble oxygenated compounds and processes | L'Oréal (FR) | 2007-02-28 | — | — | EP | claimed |
| EP-1430876-A1 | Composition containing a direct dyestuff and a specific polymer for colouring of keratinic fibres, method for the preparation thereof and process of dyeing with such a composition | L'OREAL (FR) | 2004-06-23 | — | — | EP | claimed |
| EP-4362906-A1 | COMPOSITION COMPRISING SHEA, AN ALKYL(POLY)GLYCOSIDE, A POLYSACCHARIDE AND A DYE | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-4362894-A1 | COMPOSITION COMPRISING N,N-DICARBOXYMETHYLGLUTAMIC ACID, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE FATTY ACID, AT LEAST ONE POLYOL, AT LEAST ONE ALKALINE AGENT AND OPTIONALLY AT LEAST ONE DYE | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-4362892-A1 | COMPOSITION COMPRISING AT LEAST ONE ALKYL (POLY)GLYCOSIDE, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE FATTY ACID, AND AT LEAST ONE ALKALINE AGENT | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-4362895-A1 | COMPOSITION COMPRISING PROPANE-1,3-DIOL, AT LEAST ONE ALKANOLAMINE, AT LEAST ONE FATTY SUBSTANCE AND OPTIONALLY AT LEAST ONE POLYOL | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-4362897-A1 | COMPOSITION COMPRISING AT LEAST NONIONIC SURFACTANT, 1,3-PROPANEDIOL, AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE COLOURING AGENT | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-4362893-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE ALKYL (POLY)GLYCOSIDE, N,N-DICARBOXYMETHYLGLUTAMIC ACID, PROPANE-1,3-DIOL, AT LEAST ONE FATTY SUBSTANCE OTHER THAN FATTY ACIDS, AT LEAST ONE DYE | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-4362896-A1 | COMPOSITION COMPRISING N,N-DICARBOXYMETHYLGLUTAMIC ACID, 1,3-PROPANEDIOL, AT LEAST ONE NONIONIC SURFACTANT, AT LEAST ONE ALKALINE AGENT AND/OR AT LEAST ONE DYE | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-1380820-A1 | Procedure of determining the composition of a dyeing product | L'OREAL S.A. (FR) | 2004-01-14 | — | — | EP | disclosed |
| US-20030152534-A1 | Composition for dyeing keratin fibers comprising a particular aminosilicone | L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | disclosed |
| US-20030140429-A1 | Keratin fibre dyeing composition comprising a particular aminosilicone | L'OREAL S.A. (FR) | 2003-07-31 | — | — | US | disclosed |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | L'OREAL S.A. (FR) | 2003-06-12 | — | — | US | disclosed |
| EP-1312343-A2 | Dyeing composition for keratinous fibres containing aminosilicone | L'OREAL S.A. (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1312344-A2 | Dyeing composition for keratinous fibres containing aminosilicone | L'OREAL (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1297819-A2 | Composition for dyeing keratinous fibres comprising a cationic azo dye | L'OREAL (FR) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | KRT18, TUBB3, TUBB1 | MAPT 468/4885ALDH1A1 2065/4885MAPK1 1531/4885 |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | KRT18, DSG1, PLOD2 | MAPT 645/4885ALDH1A1 188/4885MAPK1 852/4885 |
| US-20030152534-A1 | Composition for dyeing keratin fibers comprising a particular aminosilicone | KRT18, TUBB8, TUBA8 | MAPT 1587/4885ALDH1A1 1914/4885MAPK1 1038/4885 |
| US-20030140429-A1 | Keratin fibre dyeing composition comprising a particular aminosilicone | KRT18, TUBB3, TUBA3E | MAPT 578/4885ALDH1A1 1615/4885MAPK1 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.