SCHEMBL7823732

SCHEMBL7823732

CCOc1cccc2c1C(=N)NC2(OCC)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.42
ALDH1A1 P00352 3/20 0.35
GRK6 P43250 1/20 0.34
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
IGF1R P08069 1/20 0.33
DAO P14920 1/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
MAPT P10636 3/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GLA P06280 1/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
APAF1 O14727 1/20 0.32
USP2 O75604 1/20 0.32
GAA P10253 1/20 0.32
THRB P10828 1/20 0.32
CASP1 P29466 1/20 0.32
BRCA1 P38398 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7827247 0.92 PDK2 (0.36) PDK2L3MBTL1MAPTNPSR1TDP1
SCHEMBL7822891 0.90 CYP1A2 (0.38) PDK2L3MBTL1TDP1TP53TSHR
SCHEMBL7827148 0.90 PDK2 (0.35) PDK2ALDH1A1KDM4EKMT2A
SCHEMBL7824104 0.89 PDK2 (0.43) PDK2ALDH1A1GRK6DDB1CRBN
SCHEMBL7828606 0.88 PRKCA (0.40) PDK2L3MBTL1MAPTNPSR1MEN1
SCHEMBL7827899 0.88 PRKCA (0.40) PDK2L3MBTL1MAPTNPSR1MEN1
SCHEMBL7815754 0.86
SCHEMBL7826141 0.85 PDK2 (0.32) PDK2
SCHEMBL7826590 0.85 LTA4H (0.34) PDK2ALDH1A1L3MBTL1NPSR1KMT2A
SCHEMBL7827488 0.79 MCHR1 (0.35) PDK2L3MBTL1MAPTNPSR1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
CN-1114431-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS (JP) 1996-01-03 CN disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed